Santos, DomingosCaseiro, Nuno2018-10-162018-10-162015Santos, D., & Caseiro, N. (2015). The Challenges of Smart Specialization Strategies and the Role of Entrepreneurial Universities: A New Competitive Paradigm. In L. Carmo Farinha, J. Ferreira, H. Smith, & S. Bagchi-Sen (Eds.), Handbook of Research on Global Competitive Advantage through Innovation and Entrepreneurship. Hershey, IGI Global, (pp. 537-551).9781466683488http://hdl.handle.net/10400.11/6240This chapter explores the relation between the concepts of entrepreneurial universities (EU) within the framework of Smart Specialization Strategies (S3). The latter is arising as a new competitive paradigm and universities can be of great importance for its successful implementation because of their contribution both as a partner institution, policy actor and producer of knowledge and social capital that can affect the potential for economic growth and development of regions. The links and contributions of both dimensions are presented and explored. As a final point, the concept of entrepreneurial ecosystem is presented as a consequence and future development of the dynamics resulting S3 and entrepreneurial universities interactions.engSmart specialisation strategiesEntrepreneurial UniversityEntrepreneurship PolicyInnovation Policybook part10.4018/978-1-4666-8348-8.ch029