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- What’s new about sample quality in routine coagulation testing?Publication . Freitas, FranciscoToday, laboratories are very much different than they were decades ago. They have improved instruments to work with, multiple off-site collection points, more competent personnel, a greater analyte panel and quality requirements for those analytes. Nevertheless, sample quality has to be assured along the total testing process (TTP) in order to guarantee reliable results to the patient. In routine coagulation, prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen (Fbg) and D-dimer are the essential part of the test panel, for which new evidences about sample quality requirements have been presented in recent years.