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Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: a study protocol for a randomized controlled trial

2022Journal article Open access
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dc.contributor.authorFerreira, José Pedro
dc.contributor.authorDuarte-Mendes, Pedro
dc.contributor.authorTeixeira, Ana
dc.contributor.authorSilva, Fernanda
dc.date.accessioned2022-10-27T13:09:15Z
dc.date.available2022-10-27T13:09:15Z
dc.date.issued2022
dc.description.abstractBackground Both physical inactivity and sedentary behavior are considered modifiable risk factors for chronic diseases and all-cause mortality. Adult office-workers spend most of their working day in sedentary behaviors, so they are particularly at high risk of developed chronic diseases (e.g., cardiovascular diseases, metabolic disorders like diabetes mellitus, . . .). It seems important to promote behavioral changes that could prevent or delay metabolic disease development. Evidence supports the use of exercise programs, however, to date there are several knowledge gaps and inconsistencies in the literature regarding the effects of Combined Training (i.e., aerobic plus resistance training) in sedentary healthy adults. This paper outlines an RCT designed to evaluate the effects of a 16-week combined training program on biochemical and immune markers of metabolic disease, lung function, salivary stress hormones and subjective quality of life (primary outcomes), as well as on body composition and physical fitness (secondary outcomes) in sedentary middle-aged office-workers. Furthermore, we aimed to assess the associations between the changes promoted by the exercise program and the different variables studied. Methods and design This is a single-blinded two-arm RCT with parallel groups. A minimum of healthy 40 officeworkers aged 40–64 years will be recruited to engage in a 16-week intervention study. After baseline assessments, participants will be randomized to one of the two groups: (1) combined training group or (2) control group. Baseline assessments will be repeated after 8 weeks of intervention (mid-testing) and upon completion of the intervention (post-testing). Discussion This RCT involves a multi-disciplinary approach and seems to be a relevant contribution to understanding the potential role of combined training in improving the metabolic profile, lung function, stress, and quality of life in adults. The results can provide important insights for clinical recommendations and for the optimization of strategies to prevent metabolic disorders in adults with sedentary jobs.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira JP, Duarte-Mendes P, Teixeira AM, Silva FM (2022) Effects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: a study protocol for a randomized controlled trial. PLoS ONE 17(2): e0263455. https://doi.org/10.1371/journal.pt_PT
dc.identifier.doi10.1371/journal.pone.0263455pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.11/8149
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationF.M.S is a grant holder from the Portuguese Foundation for Science and Technology (2020.08759.BD). The funder had no role in the development of the protocol, preparation of the manuscript, or the decision to submit for publication.pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectResistance trainingpt_PT
dc.subjectRandomized controlled trialspt_PT
dc.subjectQuality of lifept_PT
dc.subjectSedentary behaviorpt_PT
dc.subjectResearch protocolspt_PT
dc.subjectDisease risk factorspt_PT
dc.titleEffects of combined training on metabolic profile, lung function, stress and quality of life in sedentary adults: a study protocol for a randomized controlled trialpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.startPagee0263455pt_PT
oaire.citation.titlePLOS ONEpt_PT
oaire.citation.volume17pt_PT
person.familyNameLeitão Ferreira
person.familyNameDuarte-Mendes
person.familyNameMiranda Botelho Teixeira
person.familyNameAntunes da Silva
person.givenNameJosé Pedro
person.givenNamePedro
person.givenNameAna Maria
person.givenNameFernanda Maria
person.identifierrid7830
person.identifier.ciencia-id661D-14B5-A499
person.identifier.ciencia-idBB19-DC8E-05C7
person.identifier.ciencia-id4B15-EC24-6644
person.identifier.ciencia-id3B13-1E85-181F
person.identifier.orcid0000-0002-4427-3276
person.identifier.orcid0000-0001-5055-2696
person.identifier.orcid0000-0003-1498-949X
person.identifier.orcid0000-0001-8019-0729
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication29bf49eb-3e65-4660-b604-6936f7d68afa
relation.isAuthorOfPublicationc4872844-d6f5-49d8-891c-a1a13e00ffc6
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relation.isAuthorOfPublication21bba01a-01a5-4aab-83b4-ff740fb29219
relation.isAuthorOfPublication.latestForDiscoveryc4872844-d6f5-49d8-891c-a1a13e00ffc6

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