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Advisor(s)
Abstract(s)
Introdução
A função do ventrículo direito é o principal
determinante do prognóstico na hipertensão
pulmonar. Esta enfermidade, definida pelo aumento
da pressão nas artérias pulmonares, tem como
consequências o remodelamento e disfunção do
ventrículo direito.
Objetivo
Avaliar as características morfológicas e fisiológicas
do coração direito em doentes com hipertensão
pulmonar.
Materiais e Métodos
Estudo observacional, transversal, de abordagem
quantitativa, com recurso a uma amostragem não
probabilística por conveniência, realizado entre 1
de agosto e 31 de dezembro de 2018 no serviço de
Cardiopneumologia de um Hospital da região centro
de Portugal. Todos os sujeitos foram submetidos
à realização de um ecoDoppler cardíaco. Foram
registados parâmetros ecocardiográficos como a
excursão sistólica do plano anular tricúspide, pressão
sistólica da artéria pulmonar, bem como o tamanho e
função das cavidades cardíacas.
Resultados
A amostra do estudo foi composta por 100
indivíduos, divididos em dois grupos: 50 saudáveis
e 50 doentes portadores de hipertensão pulmonar,
com idades superiores a 40 anos e ausência de outra
patologia cardíaca conhecida ou hipertensão arterial
severa. No que diz respeito à função sistólica do
ventrículo direito, esta apresenta-se mais elevada
nos indivíduos saudáveis, sendo essa diferença
estatisticamente significativa (p<0,001) embora,
em média, apresente valores normais nos doentes
com patologia. As cavidades cardíacas apresentamse significativamente dilatadas na presença da
doença (p<0,001), à exceção do ventrículo esquerdo
(p-value=1). Relativamente à função diastólica
esta apresenta uma relação inversa com a pressão
sistólica da artéria pulmonar, ou seja, esta é tanto
menor quanto melhor se apresentar a função de
ambos os ventrículos (p<0,001).
Conclusão:
Foi encontrada evidência de que, com base nos
parâmetros ecocardiográficos nesta amostra de
doentes, a hipertensão pulmonar provoca disfunção
ventricular direita e dilatação das câmaras direitas.
Isto reforça a necessidade de prevenção, identificação
e intervenção precoces nestes indivíduos.
ABSRACT: Introduction Right ventricular function is the main determinant of the prognosis in pulmonary hypertension. This disease, defined by increased pressure in the pulmonary arteries, has the consequences of remodeling and dysfunction of the right ventricle. Objective To evaluate the morphological and physiological characteristics of the right heart in patients with pulmonary hypertension. Materials and Methods This cross-sectional observational study was carried out using a non-probabilistic sampling for convenience. All subjects underwent an echocardiogram. Echocardiographic parameters such as systolic excursion of the tricuspid annular plane, systolic pulmonary artery pressure, as well as the size and function of the cardiac cavities were recorded. Results The study sample consisted of 100 individuals, divided into two groups: 50 healthy and 50 patients with pulmonary hypertension, aged over 40 years and with no other known cardiac pathology or severe arterial hypertension. With regard to the systolic function of the right ventricle, it is higher in healthy individuals, with a statistically significant difference (p <0.001) although, on average, it presents normal values in patients with pathology. The cardiac chambers are significantly dilated in the presence of the disease (p <0.001), with the exception of the left ventricle (p-value = 1). Regarding the diastolic function, it has an inverse relationship with the systolic pressure of the pulmonary artery, that is, the lower the better the function of both ventricles (p <0.001). Conclusion Evidence was found that, based on echocardiographic parameters in this sample of patients, pulmonary hypertension causes right ventricular dysfunction and dilation of the right chambers. This reinforces the need for early prevention, identification and intervention in these individuals.
ABSRACT: Introduction Right ventricular function is the main determinant of the prognosis in pulmonary hypertension. This disease, defined by increased pressure in the pulmonary arteries, has the consequences of remodeling and dysfunction of the right ventricle. Objective To evaluate the morphological and physiological characteristics of the right heart in patients with pulmonary hypertension. Materials and Methods This cross-sectional observational study was carried out using a non-probabilistic sampling for convenience. All subjects underwent an echocardiogram. Echocardiographic parameters such as systolic excursion of the tricuspid annular plane, systolic pulmonary artery pressure, as well as the size and function of the cardiac cavities were recorded. Results The study sample consisted of 100 individuals, divided into two groups: 50 healthy and 50 patients with pulmonary hypertension, aged over 40 years and with no other known cardiac pathology or severe arterial hypertension. With regard to the systolic function of the right ventricle, it is higher in healthy individuals, with a statistically significant difference (p <0.001) although, on average, it presents normal values in patients with pathology. The cardiac chambers are significantly dilated in the presence of the disease (p <0.001), with the exception of the left ventricle (p-value = 1). Regarding the diastolic function, it has an inverse relationship with the systolic pressure of the pulmonary artery, that is, the lower the better the function of both ventricles (p <0.001). Conclusion Evidence was found that, based on echocardiographic parameters in this sample of patients, pulmonary hypertension causes right ventricular dysfunction and dilation of the right chambers. This reinforces the need for early prevention, identification and intervention in these individuals.
Description
Keywords
Ecocardiografia Ventrículos do coração Aurículas cardíacas Hipertensão pulmonar Echocardiography Heart ventricles Heart atria Pulmonary hypertension
Citation
LOPES, Ângela; ALCAFACHE, Carlos; MOTA, Mauro (2020) - Avaliação da função ventricular direita na hipertensão pulmonar. HIGEIA : Revista Científica da Escola Superior de Saúde Dr. Lopes Dias. ISSN 2184-5565. Ano 2, vol. 3, nº 1, p. 69-79.
Publisher
IPCB. ESALD