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End of OSLER test sessions in Parkinson’s disease do not correspond to true sleep onset: Results from an exploratory study
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Advisor(s)
Abstract(s)
The aim of the present study was to evaluate the correlation between the end of an Oxford
sleep resistance (OSLER) test session and a neurophysiological marker of sleep onset in
Parkinson’s disease (PD) patients. Single center study was conducted in PD patients
with excessive daytime sleepiness [Epworth sleepiness scale (ESS) >9]. The OSLER test
was conducted with a concomitant electroencephalography (EEG), electromyography
(mentalis), right and left electroculogram, and video monitoring. Neurophysiological (NP)
sleep onset was defined according to AASM criteria (2005). Five PD patients with mean
ESS of 14 (10–16) were included. OSLER test duration was shorter than 40 min in all
patients (mean duration 20 min and 39 s). No patient fulfilled neurophysiological criteria to
sleep onset at the time of OSLER test termination. In 13 OSLER sessions that ended
before 40 min, eight had microsleeps in the last 30 s before the end of the test. NP
monitoring showed signs of sleepiness in all patients. In PD patients, the early termination
of an OSLER test session may not correspond to NP criteria of sleep onset. However, in
all PD patients with abnormal OSLER results, there were EEG signs of sleepiness, which
do not exclude the potential utility of OSLER test to evaluate the risk of falling asleep.
Description
Keywords
Sleepiness Sleep onset OSLER test Parkinson’s disease
Pedagogical Context
Citation
NEUTEL, D. [et al.] (2015) - End of OSLER test sessions in Parkinson’s disease do not correspond to true sleep onset: results from an exploratory study. Frontiers in Neurology. 6:200. DOI: 10.3389/fneur.2015.00200