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Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents

2023Journal article Open access
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dc.contributor.authorDomingues, Joana Lopes
dc.contributor.authorGoulão, Manuela
dc.contributor.authorDelgado, F.M.G.
dc.contributor.authorGonçalves, José Carlos
dc.contributor.authorGonçalves, Joana
dc.contributor.authorPintado, Cristina Santos
dc.date.accessioned2023-04-18T12:05:12Z
dc.date.available2023-04-18T12:05:12Z
dc.date.issued2023
dc.date.updated2023-04-11T15:09:27Z
dc.description.abstractChemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability) in NHDF cells at all concentrations tested.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDOMINGUES, Joana [et al.] (2023) - Essential oils of two Portuguese endemic species of lavandula as a source of antifungal and antibacterial sgents. Processes. 11, 1165. DOI https:// doi.org/10.3390/pr11041165pt_PT
dc.identifier.doi10.3390/pr11041165pt_PT
dc.identifier.slugcv-prod-3230846
dc.identifier.urihttp://hdl.handle.net/10400.11/8455
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation0665_COOP4PAM_4_Ppt_PT
dc.relationUID/AMB/00681/2013pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectL. stoechas subsp. luisieript_PT
dc.subjectL. pedunculatapt_PT
dc.subjectChemical profilept_PT
dc.subjectAntimicrobial activitypt_PT
dc.subjectCytotoxicitypt_PT
dc.titleEssential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agentspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage12pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleProcessespt_PT
oaire.citation.volume11pt_PT
person.familyNameDelgado
person.familyNameGonçalves
person.familyNameSantos Pintado
person.givenNameFernanda
person.givenNameJosé
person.givenNameCristina Maria Baptista
person.identifier508085
person.identifier.ciencia-idC715-76B6-A07D
person.identifier.ciencia-idAE1F-12BE-65DD
person.identifier.ciencia-id7F1F-E7E1-5BC6
person.identifier.orcid0000-0003-1238-9386
person.identifier.orcid0000-0003-3387-4487
person.identifier.orcid0000-0001-5433-4258
person.identifier.scopus-author-id7103325479
person.identifier.scopus-author-id6602633775
rcaap.cv.cienciaidC715-76B6-A07D | Fernanda Delgado
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication8ae072f8-0aa1-46ce-830a-210c42f9e11b
relation.isAuthorOfPublication3f401604-ccbb-45f3-8ee1-05063cf3d60a
relation.isAuthorOfPublicatione5822f39-6e57-4619-b731-b51b3026cdfe
relation.isAuthorOfPublication.latestForDiscovery3f401604-ccbb-45f3-8ee1-05063cf3d60a

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