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Fourier transform infrared (FT-IR) spectroscopy typing: a real-time analysis of an outbreak by carbapenem-resistant Klebsiella pneumoniae
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Autores
Orientador(es)
Resumo(s)
The spread of multidrug-resistant (MDR) Klebsiella pneumoniae in the nosocomial setting represents a big challenge to infection control teams. We have recently developed a simple spectroscopic-based method with excellent accuracy, turnaround time and cost-effectiveness (Rodrigues et al. mSystems 2020) for bacterial typing. Here, we applied our method in a real clinical context to support early identification of an outbreak involving KPC-3-producing K. pneumoniae ST147 isolates. Our results further support that attenuated total reflectance Fourier transform infrared (FT-IR) spectroscopy can provide enough information to support early and adequate infection control measures and therapeutic choices in the context of nosocomial outbreaks and hospital surveillance.
Descrição
Palavras-chave
Bacterial typing Nosocomial infection Carbapenemases KPC-3 Capsule type Capsular polysaccharides
Contexto Educativo
Citação
SILVA, L. [et al.] (2020) - Fourier transform infrared (FT-IR) spectroscopy typing: a real-time analysis of an outbreak by carbapenem-resistant Klebsiella pneumoniae. European Journal of Clinical Microbiology & Infectious Diseases. ISSN 0934-9723. Vol. 39, p.2471–2475 . DOI: 0.1007/s10096-020-03956-y
Editora
Springer Nature