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Talaromyces marneffeiisolated from nasal swabs in Portugal
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Orientador(es)
Resumo(s)
Mycobiota are essential to the health of any living being,
creating a balanced and complex interaction between
bacteria, the immune system, and the tissue cells of the host.
Talaromyces marneffei (also known as Penicillium marneffei) is
a dimorphic fungus, endemic in South Asia, which often
causes a life-threatening systemic fungal infection (called
penicilliosis), particularly in immunocompromised hosts.
Nasal swabs from 73 healthy volunteers were analysed to
characterize their mycobiota, through its cultural
characteristics, morphology, and molecular methods (PCR).
All volunteers were also asked to answer to an anonymous
questionnaire. Three women were positive (and
asymptomatic) for T. marneffei. One of them was reported to
have lupus. This study contributes to improving our
knowledge about human normal mycobiota, identifying
mycotic agents that may cause complicated systemic
infections (as T. marneffei), especially in immunosuppressed
patients, as well as other possible risk factors of exposure or
prognosis.
Descrição
Palavras-chave
Fungi Mycobiota Nasal mucosa Talaromyces marneffiei Penicilliosis
Contexto Educativo
Citação
MATOS, Catarina Jota Baptista [et al.] (2023) - Talaromyces marneffei isolated from nasal swabs in Portugal. Medical Mycology. Vol. 61, Issue 4, myad031. DOI: https://doi.org/10.1093/mmy/myad031